Department of General Surgery, Faculty of Medicine, Menoufia University, Menoufia, Egypt
10.21608/asjs.2025.413616.1229
Abstract
Introduction: For individuals with locally advanced, multi-focal or multi-centric breast cancer (MFMC), extreme oncoplastic breast conservation surgery (EOBCS) may be a possibility. By improving esthetic results and oncological safety, Extreme Oncoplasty (EO) expands the indications of breast conservative surgery (BCS) for patients who would otherwise need mastectomy. Aim of work: To study the feasibility of extreme oncoplastic surgery for conservation of breast in locally advanced multifocal and multicentric breast courser. Patients and methods: The study is prospective and retrospective, and comprised 40 patients who presented to Menoufia University Hospitals between 2020 and 2024 with tumors ≥ 50 mm or who had MF/MC in two adjacent quadrants. Therapeutic Reduction Mammoplasty (TRM) with immediate or delayed contralateral symmetry was provided to patients with big ptotic breasts (cup D). Lateral mammaplasty procedures were offered to patients with medium-sized breasts (cup B, C) with the same tumor criteria. Results: Forty patients were included in the study with a median age of 55 years (range 37-70). Clear margins were achieved in 39 (97.5%) patients, 1 (2.5%) patient showed inadequate margins at final histopathology analysis and required a completion mastectomy. None of participants got major complications. Minor complications as delayed healing of wound (17.5%), wound infection and dehiscence that required antibiotics (7.5%), seroma (7.5%), all managed conservatively. Regarding score of satisfaction, were (excellent) in 17 cases (42.5%), (good) in 21 cases (52.5%), and (fair) in 2 cases (5%). Conclusion: For patients with breast cancer whose tumors are ≥ 50 mm or MF/MC, extreme oncolastic surgery is a good option with a low rate of complications and high patient satisfaction. So, it may be regarded as an oncologically safe alternative to mastectomy.
Shahin, M., Alsisy, A., & Alhanafy, M. (2025). Extreme Oncoplastic Surgery for Conservation of Breast in Locally Advanced, Multifocal and Multicentric Breast Cancer. Ain Shams Journal of Surgery, 18(4), 362-367. doi: 10.21608/asjs.2025.413616.1229
MLA
Mahmoud Ahmed Shahin; Alaa Abdelazeem Alsisy; Mohamed Kamal Alhanafy. "Extreme Oncoplastic Surgery for Conservation of Breast in Locally Advanced, Multifocal and Multicentric Breast Cancer", Ain Shams Journal of Surgery, 18, 4, 2025, 362-367. doi: 10.21608/asjs.2025.413616.1229
HARVARD
Shahin, M., Alsisy, A., Alhanafy, M. (2025). 'Extreme Oncoplastic Surgery for Conservation of Breast in Locally Advanced, Multifocal and Multicentric Breast Cancer', Ain Shams Journal of Surgery, 18(4), pp. 362-367. doi: 10.21608/asjs.2025.413616.1229
VANCOUVER
Shahin, M., Alsisy, A., Alhanafy, M. Extreme Oncoplastic Surgery for Conservation of Breast in Locally Advanced, Multifocal and Multicentric Breast Cancer. Ain Shams Journal of Surgery, 2025; 18(4): 362-367. doi: 10.21608/asjs.2025.413616.1229
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